Modulation of Cardiac Calcium Sensitivity: A New Approach to Increasing the Strength of the Heart John A. Lee

ISBN: 9780192623478

Published: April 29th 1993

Hardcover

368 pages


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Modulation of Cardiac Calcium Sensitivity: A New Approach to Increasing the Strength of the Heart  by  John A. Lee

Modulation of Cardiac Calcium Sensitivity: A New Approach to Increasing the Strength of the Heart by John A. Lee
April 29th 1993 | Hardcover | PDF, EPUB, FB2, DjVu, audiobook, mp3, RTF | 368 pages | ISBN: 9780192623478 | 4.16 Mb

Calcium sensitizers are a new class of drug which increases the force of contraction of the heart by increasing the calcium sensitivity of contractile proteins. Their development represents the first major innovation in the treatment of heart failureMoreCalcium sensitizers are a new class of drug which increases the force of contraction of the heart by increasing the calcium sensitivity of contractile proteins.

Their development represents the first major innovation in the treatment of heart failure for over 200 years. Unlike other drugs in this area, they do not increase the intracellular calcium concentration and do not have the side effects associated with that mechanism of action.

These drugs offer an exciting alternative approach to the treatment of heart failure, and this volume provides an authoritative overview of the physiology, biochemistry, and clinical issues involved. It will be of interest to pharmacologists, research and clinical cardiologists, and physiologists.



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